Multicentric Reticulohistiocytosis Can Mimic Rheumatoid Arthritis

Multicentric Reticulohistiocytosis: A Reason for Erosive Arthritis

Multicentric Reticulohistiocytosis (MRH) is a rare histiocytic disorder that primarily involves the skin and joints but can affect multiple visceral organs. A female patient presented a characteristic papulonodular skin eruption and polyarthritis with positive Antinuclear Antibody (ANA), and skin biopsy findings demonstrated classic features of MRH. The patient’s clinical manifestations were in...

Multicentric Reticulohistiocytosis Presenting with Papulonodular Skin Lesions and Arthritis Mutilans

Multicentric reticulohistiocytosis is a rare multisystem disorder of unknown etiology that is characterized by erosive polyarthritis and papulonodular lesions on the skin, mucous membranes, and internal organs. We report the case of a 54-year-old female who was misdiagnosed as having rheumatoid arthritis and underwent numerous joint replacement surgeries for progressively destructive arthritis ...

Progressive multicentric reticulohistiocytosis.

Organizing pneumonia associated with multicentric reticulohistiocytosis

Organizing pneumonia (OP) is a clinicopathological entity that occurs idiopathically or in association with several conditions such as connective tissue diseases. Multicentric reticulohistiocytosis (MRH) is a systemic disease characterized by polyarthritis and mucocutaneous lesions, but lung involvement is uncommon. We report a patient with MRH associated with OP. This case may be of interest w...

Multicentric Reticulohistiocytosis with Dermatomyositis-like Eruptions

A 68-year-old man presented with polyarthritis, proximal muscle weakness, and erythema of the face, arms, neck, and anterior chest that resembled the V-neck sign. Initially, dermatomyositis (DM) was considered because of the erythema, polyarthritis, and muscle weakness. He also had mediastinal and hilar lymphadenopathy on contrast-enhanced computed tomography. Unexpectedly, a biopsy of the fore...